The malignant signature gene of cancer-associated fibroblasts serves as a potential prognostic biomarker for colon adenocarcinoma patients
BackgroundColon adenocarcinoma (COAD) is the most frequently occurring type of colon cancer.Cancer-associated fibroblasts (CAFs) are pivotal in facilitating tumor growth and metastasis; however, their specific role in COAD is not yet fully understood.This research utilizes single-cell RNA sequencing (scRNA-seq) to identify and validate gene markers